Their structures were elucidated based on the analysis of their nmr and ms data. Constituents from nauclea latifolia with antihaemophilus. Nauclea latifolia, also named nauclea esculentus, is one of the medicinal plants used in africa. Nauclea latifolia smith belongs to the family rubiaceae. Antiulcerogenic and gastric antisecretory effects of. Science and education publishing is an academic publisher of open access journals. Nauclea latifolia rubiaceae commonly known as pin cushion tree is. Only 10% of plants have been studied for their pharmacological properties. The stem bark, the leaves, the roots, and the fruit of this plant are used to treat various types of. Nauclea latifolia has an open canopy and terminal spherical head lined cymes of white flowers. The effect of nauclea latifolia leaf extract on some biochemical parameters in streptozotocin diabetic rat models 1effiong, grace sylvester and 2akpan, henry dan.
Nauclea latifolia is an evergreen tree with multiple stems and adapts very well in both the tropical rainforest zone and the savanna woodlands situated in the west and central africa. In vivo and in vitro studies were conducted to determine possible anthelmintic effect of leaf extracts of nauclea latifolia toward different ovine gastro intestinal nematodes. Latifolia is native to africa and asia gidado et al. The effect of nauclea latifolia, a promising vegetable used in the traditional management of metabolic disorders on some biochemical assay was investigated in diabetic rat. Nauclea latifolia contained alkaloid, saponins, flavonoids, cardiac glycosides and steroids while tannins and terpenoids were absent.
The effect of nauclea latifolia leaf extract on alpha. It bears spherical clusters of fragrant flowers that develop into golf ballsized edible but. Extracts of the plant have exhibited activity against escherichia coli, shigella flexneri, salmonella typhi and staphylococcus aureus which are responsible for gastroenteritis in children. Nauclea latifolia aqueous leaf extract eliminates hepatic and. A research paper, showing the presence of a natural painrelieving opoid in the bark and roots of nauclea latifolia.
The study design consisted of twenty four rats divided into four groups of six rats each. The effect of nauclea latifolia leaf extract on some. Nauclea is a genus of flowering plants in the family rubiaceae. It refers to the resemblance of the cells of the capsule to a ships hull. Leaf extracts extenuates free radicals, inflammation, and diabeteslinked enzymes franklyn nonso iheagwam,1,2 emmanuel nsedu israel,1 kazeem oyindamola kayode,1 opeyemi christianah decampos,1,2 olubanke olujoke ogunlana,1,2 and shalom nwodo chinedu1,2. Nauclea orientalis herb uses, benefits, cures, side. African peach is also commonly known as african fig and is a member of the rubiaceae coffee family of flowering plants. Dec 03, 2017 nauclea latifolia stem bark has been found to contain tramadol, a strong pain killer in its natural form. Three new indole alkaloids, named naucleamide g 1, and nauclealomide b and c 5 and 6, were isolated from the nbuohsoluble fraction of an etoh extract of the leaves of nauclea officinalis, together with three known alkaloids, paratunamide c 2, paratunamide d 3 and paratunamide a 4.
It normally produces interesting flowers, edible, but not appealing, large red ball fruits with long projecting stamens. Leaves elliptical, shortly acuminate, obtusely narrowed or nearly rounded at the base, with about 78 lateral veins on each side, 28 by 14 in petiole 15 45 in stipules short, obtuse, keeled, minutely ciliate. Leaves elliptical, shortly acuminate, obtusely narrowed or nearly rounded at the base, with about 78 lateral veins on each side, 28 by 14 in petiole 15 45 in. List of various diseases cured by nauclea orientalis. Traditional medicine in many areas of the world relies on the use of a wide variety of plant species. Pin cushion tree, african peach, guinea peach, sierra leone peach. How nauclea orientalis is effective for various diseases is listed in repertory format. Sep 07, 2010 all animals had free access to tap water and food, except for short fasting period before oral administration of single doses of the decoction of the roots of nauclea latifolia. Nauclea latifolia stem bark has been found to contain tramadol, a strong pain killer in its natural form. Rubiaceae locally nicknamed chloroquine leaf is an evergreen multistemmed medicinal plant. Nov 04, 2014 this page was last edited on 20 december 2019, at 14. Nauclea latifolia is a deciduous tree growing to 10 m 32ft by 10 m 32ft at a medium rate. This tree is known to have various medical uses, particularly by folk medicine men 5. Nauclea latifolia extract in hot water, cold water, petroleum ether and.
Nauclea latifolia smith rubiaceae is a multistemmed shrub or small tree which is widespread in tropical africa and asia. Indole alkaloids from the leaves of nauclea officinalis. Research article study on the antioxidant potentials of the. It bears an interesting flower, large red ball fruit with long projecting stamens. Antipyretic and antinociceptive effects of nauclea.
Commonly used parts of nauclea latifolia include the leaves, roots, stem, and fruits. Rubiaceae is a straggling, evergreen, multistemmed shrub or small tree native to tropical africa and asia. Histomophological study of the effect of ethanolic extract. Free radicals, which belong to a group of reactive oxygen. The terminal vegetative buds are usually strongly flattened. Files are available under licenses specified on their description page. Nauclea is a member of the tribe naucleeae and is sister to a clade consisting of burttdavya and sarcocephalus. Nauclea latifolia african peach pfaf plant database.
Uses, benefits, cures, side effects, nutrients in nauclea orientalis. Despite the acclaimed and documented uses of nauclea latifolia there appears to be a paucity of information on the safety of this plant on the neonatal kidney, as traditional birth attendant in nigeria have used the ethanolic extract of nauclea latifolia stem and root bark in arresting preterm contractions in pregnant women duke, 2008. It is commonly known as pin cushion tree being a straggling shrub or small tree, native to the tropical africa and asia 6. Nauclea latifolia smith, a shrub belonging to the family rubiaceae is a very popular medicinal plant in cameroon and neighboring countries where it is used to treat jaundice, yellow fever. The leaves are employed traditionally for the treatment of malaria in east africa1and in nigeria2. In part of nigeria, the roots of nauclea latifolia.
The stem bark, the leaves, the roots, and the fruit of this plant are used to treat various types of diseases 2, 3, 4. Hot water extracts of the leaves and fruits of nauclea latifolia were assessed. Latifolianine a 1 represents an unusual and unprecedented monoterpene indole alkaloid unit condensed with. To assess the effects of hot water leaf extract of nauclea latifolia n. In vitro study on the antioxidant potentials of the leaves. African peach trees can grow up to 30 meters in height depending on their exposure to water. It is widely distributed throughout the forest and tropical forests of benin, burkina faso, cameroon, democratic republic of congo, ghana and nigeria lamidi et al. Trolox equivalence antioxidant capacity in the aqueous extracts of the leaves and fruits of nauclea latifolia.
A glabrescent or puberulous tree with long branches or often a scandent shrub, 1025 ft. Sarcocephalus latifolius, nauclea latifolia, african peach. The teac assay is based on the suppression of the absorbance of radical cations of 2,2azinobis3ethylbenzothiazoline6sulfonate abts by antioxidants in the sample when abts incubates with a peroxidase metmyoglobin and h 2 o 2 43, 44. Research article study on the antioxidant potentials of.
The antibacterial potentials of nauclea latifolia semantic scholar. Udenigwe, wadim matochko, paul holloway, michael o. Nauclea orientalis herb uses, benefits, cures, side effects. Full length research paper antiviral effects of nauclea latifolia on newcastle disease virus ndv onu ukamaka1, nwiyi paul2 and erumaka ikechi2 1department of microbiology and brewery, nnamdi azikiwe university, awka anambra state, nigeria. Sarcocephalus latifolius, nauclea latifolia family. The current type species for the genus is nauclea orientalis. It has many common names, including bur tree, canary wood, leichhardt pine and yellow cheesewood. Research article in vitro study on the antioxidant potentials of the leaves and fruits of nauclea latifolia ademolao. Anthelmintic efficacy of nauclea latifolia extract against. May 15, 2018 african peach nauclea latifolia is a deciduous evergreen tree native to the savanna forests of continental africa.
Nauclea orientalis is a species of tree in the family rubiaceae, native to southeast asia, new guinea, and australia. The extract was administered by gavage at the doses of, 2000, 4000, 8000, 10 000, 12 000 and 14 000 mgkg or by the intraperitoneal route at the doses of 100, 250. Antipyretic and antinociceptive effects of nauclea latifolia. Names of nauclea orientalis in various languages of the world are also given. It grows to a maximum of around 30 m 98 ft in height and has large glossy leaves. Whereas groups 1 and 2, non diabetic and diabetic controls received placebo treatment, groups 3 received 200mgkg b.
The plant is used traditionally in the treatment of various diseases. Nauclea latifolia is a unique plant that has been used for the treatment of various ailments such as diabetes mellitus, malaria and hypertension. Rubiaceae is a valuable medicinal plant that is widespread in the humid tropical rainforest or in savannah woodland zone of west and central africa. In vitro study of nutritional and antioxidant properties of. Chemical constituents of nauclea latifolia and their anti. African peach nauclea latifolia is a deciduous evergreen tree native to the savanna forests of continental africa.
Tramadol, a drug formerly only thought to exist as a synthetic, has been found in nature. Hematological parameters which have been implicated in diabetes mellitus were investigated in this study. In vitro study of nutritional and antioxidant properties. Us20160039742a1 extraction of tramadol from nauclea. A larval development assay was used to investigate in vitro, the effect of aqueous and ethanolic extracts of n. Hypanthia and fruitlets can be free or connate into a syncarp.
Pdf traditional uses, phytochemistry and pharmacological. This study was carried out to investigate the in vitro antioxidant potentials of the leaves and fruits of nauclea latifolia, a straggling shrub or small tree, native to tropical africa and asia. African tree, nauclea latifolia, contains tramadol on. Results percentage yield of methanol in rootbark extract of nauclea latifolia smith extraction of 500 g finely ground crude sample of nauclea latifolia rootbark with 1. Evaluation of antidiabetic activity of nauclea latifolia. Three previously undescribed indole alkaloids, named latifolianine a 1 and latifoliaindoles a and b 2 and 3, along with 10 known compounds 4, were isolated from the heartwood of nauclea latifolia. Direct effects of nauclea latifolia extracts on different gastrointestinal nematodes of sheep is described.
Also known as pin cushion tree and bishops head, it is a struggling shrub or small tree native to tropical africa and asia 7. Nauclea latifolia is a valuable medicinal plant that is widespread in the humid tropical rainforest zone or in savannah woodlands of west and central africa. The structures with absolute configurations of the new compounds were identified on the basis of 1d. The generic name is derived from the ancient greek words naus, meaning ship and kleio, meaning to close. Nauclea latifolia is used a lot in nigeria especially in the southwest part due to its. The percentage glycaemic change on nondiabetic rats following. Chemical constituents of nauclea latifolia and their antigst and antifungal activities athar ata, chibuike c. Nauclea latifolia is in stock with a 4 ounce limit, per customer, per order. Leaf extracts extenuates free radicals, inflammation, and diabeteslinked enzymes franklyn nonso iheagwam,1,2 emmanuel nsedu israel,1 kazeem oyindamola kayode,1 opeyemi christianah decampos,1,2 olubanke olujoke ogunlana,1,2 and shalom nwodo chinedu1,2 1department of biochemistry, covenant university, canaanland, p.
A process for obtaining cis2dimethylaminomethylmethoxyphenylcyclohexanol includes the following steps. Linnaeus originally named it cephalanthus orientalis in the first edition of species plantarum but transferred it to nauclea when he erected that genus in the second. Hot water extracts of the leaves and fruits of nauclea latifolia were assessed for their total polyphenolic, flavanol, and flavonol contents as well as 1diphenyl2picrylhydrazyl dpph scavenging. Extracts of the plant have exhibited activity against escherichia coli, shigella flexneri, salmonella typhi and staphylococcus aureus which are responsible for gastroenteritis in children303. Other uses the heartwood is a golden yellow or an orangey yellow, slightly moire it darkens slightly when exposed to light but in interior end use this colour remains stable.
This page was last edited on 20 december 2019, at 14. Aspergillus niger is a filamentous ascomycete fungus that is ubiguitous in the environment and has been implicated in opportunistic infections of humans. It also publishes academic books and conference proceedings. Table 2 shows the effect of chloroform extract of nauclea latifolia and glibenclamide on blood glucose level of nondiabetic rats. Bioactive screening and in vitro antioxidant assessment of nauclea latifolia leaf decoction franklyn nonso iheagwam 1, 2, a, emmanuel israel nsedu 1, kazeem oyindamola kayode 1, opeyemi christianah emiloju 1, 2, olubanke olujoke ogunlana 1, 2 and shalom nwodo chinedu 1, 2 1 department of biochemistry, college of science and technology, covenant university, canaanland, p. Histomophological study of the effect of ethanolic extract of. Anticonvulsant, anxiolytic, and sedative properties of the. Rubiaceae is a spreading, evergreen, multistemmed shrub or small tree native to tropical africa and asia gidado et al. In vitro study on the antioxidant potentials of the leaves and fruits of nauclea latifolia ademolao.
Chemical constituents of nauclea latifolia and their antigst. Nhexane, ethyl acetate, butanol and methanol fractions of the ethanolic leaf extract of nauclea latifolia were orally administered once daily for 2 weeks to diabetic rats. We will indeed be offering the african herb, nauclea latifolia, stephen buhner has mentioned. All animals had free access to tap water and food, except for short fasting period before oral administration of single doses of the decoction of the roots of nauclea latifolia. In vitro study on the antioxidant potentials of the leaves and fruits. Acute and subacute toxicity of aqueous extract of nauclea. This study was carried out to assess the in vitro antioxidant, antiinflammatory and antidiabetic effects of nauclea latifolia sm. Nauclea latifolia aqueous leaf extract eliminates hepatic. The species are evergreen trees or shrubs that are native to the paleotropics. A 4 ounce bottle should be close to a one month supply.