Nauclea orientalis is a species of tree in the family rubiaceae, native to southeast asia, new guinea, and australia. To assess the effects of hot water leaf extract of nauclea latifolia n. Nauclea latifolia has an open canopy and terminal spherical head lined cymes of white flowers. List of various diseases cured by nauclea orientalis. In part of nigeria, the roots of nauclea latifolia. Anthelmintic efficacy of nauclea latifolia extract against. In vitro study on the antioxidant potentials of the leaves and fruits. Only 10% of plants have been studied for their pharmacological properties. Three new indole alkaloids, named naucleamide g 1, and nauclealomide b and c 5 and 6, were isolated from the nbuohsoluble fraction of an etoh extract of the leaves of nauclea officinalis, together with three known alkaloids, paratunamide c 2, paratunamide d 3 and paratunamide a 4. Commonly used parts of nauclea latifolia include the leaves, roots, stem, and fruits. Full length research paper nauclea latifolia on newcastle.
The plant is used traditionally in the treatment of various diseases. It bears an interesting flower, large red ball fruit with long projecting stamens. Rubiaceae locally nicknamed chloroquine leaf is an evergreen multistemmed medicinal plant. Free radicals, which belong to a group of reactive oxygen. Nauclea latifolia stem bark has been found to contain tramadol, a strong pain killer in its natural form. Hypanthia and fruitlets can be free or connate into a syncarp. The structures with absolute configurations of the new compounds were identified on the basis of 1d. Nauclea latifolia extract in hot water, cold water, petroleum ether and. In vitro study of nutritional and antioxidant properties of. Uses, benefits, cures, side effects, nutrients in nauclea orientalis. Hot water extracts of the leaves and fruits of nauclea latifolia were assessed for their total polyphenolic, flavanol, and flavonol contents as well as 1diphenyl2picrylhydrazyl dpph scavenging. African peach trees can grow up to 30 meters in height depending on their exposure to water. Other uses the heartwood is a golden yellow or an orangey yellow, slightly moire it darkens slightly when exposed to light but in interior end use this colour remains stable. Extracts of the plant have exhibited activity against escherichia coli, shigella flexneri, salmonella typhi and staphylococcus aureus which are responsible for gastroenteritis in children.
Pdf traditional uses, phytochemistry and pharmacological. Names of nauclea orientalis in various languages of the world are also given. A larval development assay was used to investigate in vitro, the effect of aqueous and ethanolic extracts of n. Science and education publishing is an academic publisher of open access journals. Sep 07, 2010 all animals had free access to tap water and food, except for short fasting period before oral administration of single doses of the decoction of the roots of nauclea latifolia. All animals had free access to tap water and food, except for short fasting period before oral administration of single doses of the decoction of the roots of nauclea latifolia. Nauclea orientalis herb uses, benefits, cures, side effects. Whereas groups 1 and 2, non diabetic and diabetic controls received placebo treatment, groups 3 received 200mgkg b. The current type species for the genus is nauclea orientalis. A glabrescent or puberulous tree with long branches or often a scandent shrub, 1025 ft. Antipyretic and antinociceptive effects of nauclea latifolia. Us20160039742a1 extraction of tramadol from nauclea.
Also known as pin cushion tree and bishops head, it is a struggling shrub or small tree native to tropical africa and asia 7. It refers to the resemblance of the cells of the capsule to a ships hull. In vitro study of nutritional and antioxidant properties. Nauclea latifolia smith, a shrub belonging to the family rubiaceae is a very popular medicinal plant in cameroon and neighboring countries where it is used to treat jaundice, yellow fever. African peach nauclea latifolia is a deciduous evergreen tree native to the savanna forests of continental africa.
A process for obtaining cis2dimethylaminomethylmethoxyphenylcyclohexanol includes the following steps. Nauclea latifolia smith belongs to the family rubiaceae. Rubiaceae is a valuable medicinal plant that is widespread in the humid tropical rainforest or in savannah woodland zone of west and central africa. Research article study on the antioxidant potentials of. The generic name is derived from the ancient greek words naus, meaning ship and kleio, meaning to close. Acute and subacute toxicity of aqueous extract of nauclea. Latifolianine a 1 represents an unusual and unprecedented monoterpene indole alkaloid unit condensed with. Three previously undescribed indole alkaloids, named latifolianine a 1 and latifoliaindoles a and b 2 and 3, along with 10 known compounds 4, were isolated from the heartwood of nauclea latifolia. Research article in vitro study on the antioxidant potentials of the leaves and fruits of nauclea latifolia ademolao. The antibacterial potentials of nauclea latifolia semantic scholar. Leaves elliptical, shortly acuminate, obtusely narrowed or nearly rounded at the base, with about 78 lateral veins on each side, 28 by 14 in petiole 15 45 in. Trolox equivalence antioxidant capacity in the aqueous extracts of the leaves and fruits of nauclea latifolia. Histomophological study of the effect of ethanolic extract.
Chemical constituents of nauclea latifolia and their antigst. The effect of nauclea latifolia, a promising vegetable used in the traditional management of metabolic disorders on some biochemical assay was investigated in diabetic rat. Research article study on the antioxidant potentials of the. Pin cushion tree, african peach, guinea peach, sierra leone peach. The percentage glycaemic change on nondiabetic rats following. Nauclea latifolia is used a lot in nigeria especially in the southwest part due to its. African tree, nauclea latifolia, contains tramadol on. Nauclea latifolia is in stock with a 4 ounce limit, per customer, per order. Leaf extracts extenuates free radicals, inflammation, and diabeteslinked enzymes franklyn nonso iheagwam,1,2 emmanuel nsedu israel,1 kazeem oyindamola kayode,1 opeyemi christianah decampos,1,2 olubanke olujoke ogunlana,1,2 and shalom nwodo chinedu1,2 1department of biochemistry, covenant university, canaanland, p. Nauclea latifolia is a deciduous tree growing to 10 m 32ft by 10 m 32ft at a medium rate. Sarcocephalus latifolius, nauclea latifolia, african peach. Histomophological study of the effect of ethanolic extract of. Nauclea latifolia, also named nauclea esculentus, is one of the medicinal plants used in africa. Nov 04, 2014 this page was last edited on 20 december 2019, at 14.
This study was carried out to assess the in vitro antioxidant, antiinflammatory and antidiabetic effects of nauclea latifolia sm. Results percentage yield of methanol in rootbark extract of nauclea latifolia smith extraction of 500 g finely ground crude sample of nauclea latifolia rootbark with 1. Nauclea is a genus of flowering plants in the family rubiaceae. Full length research paper antiviral effects of nauclea latifolia on newcastle disease virus ndv onu ukamaka1, nwiyi paul2 and erumaka ikechi2 1department of microbiology and brewery, nnamdi azikiwe university, awka anambra state, nigeria. Rubiaceae is a spreading, evergreen, multistemmed shrub or small tree native to tropical africa and asia gidado et al. In vitro study on the antioxidant potentials of the leaves. The effect of nauclea latifolia leaf extract on some biochemical parameters in streptozotocin diabetic rat models 1effiong, grace sylvester and 2akpan, henry dan. Nauclea latifolia aqueous leaf extract eliminates hepatic. In vitro study on the antioxidant potentials of the leaves and fruits of nauclea latifolia ademolao. Tramadol, a drug formerly only thought to exist as a synthetic, has been found in nature. In vivo and in vitro studies were conducted to determine possible anthelmintic effect of leaf extracts of nauclea latifolia toward different ovine gastro intestinal nematodes. The species are evergreen trees or shrubs that are native to the paleotropics. The effect of nauclea latifolia leaf extract on some. The extract was administered by gavage at the doses of, 2000, 4000, 8000, 10 000, 12 000 and 14 000 mgkg or by the intraperitoneal route at the doses of 100, 250.
Anticonvulsant, anxiolytic, and sedative properties of the. Nauclea latifolia aqueous leaf extract eliminates hepatic and. Indole alkaloids from the leaves of nauclea officinalis. The stem bark, the leaves, the roots, and the fruit of this plant are used to treat various types of. Evaluation of antidiabetic activity of nauclea latifolia. Leaf extracts extenuates free radicals, inflammation, and diabeteslinked enzymes franklyn nonso iheagwam,1,2 emmanuel nsedu israel,1 kazeem oyindamola kayode,1 opeyemi christianah decampos,1,2 olubanke olujoke ogunlana,1,2 and shalom nwodo chinedu1,2. Rubiaceae is a straggling, evergreen, multistemmed shrub or small tree native to tropical africa and asia. Chemical constituents of nauclea latifolia and their anti.
Chemical constituents of nauclea latifolia and their antigst and antifungal activities athar ata, chibuike c. Nauclea orientalis herb uses, benefits, cures, side. Leaves elliptical, shortly acuminate, obtusely narrowed or nearly rounded at the base, with about 78 lateral veins on each side, 28 by 14 in petiole 15 45 in stipules short, obtuse, keeled, minutely ciliate. Dec 03, 2017 nauclea latifolia stem bark has been found to contain tramadol, a strong pain killer in its natural form. The terminal vegetative buds are usually strongly flattened. Antiulcerogenic and gastric antisecretory effects of. Udenigwe, wadim matochko, paul holloway, michael o. The leaves are employed traditionally for the treatment of malaria in east africa1and in nigeria2. Sarcocephalus latifolius, nauclea latifolia family. All structured data from the file and property namespaces is available under the creative commons cc0 license. Nauclea latifolia is a unique plant that has been used for the treatment of various ailments such as diabetes mellitus, malaria and hypertension. Antipyretic and antinociceptive effects of nauclea.
It has many common names, including bur tree, canary wood, leichhardt pine and yellow cheesewood. Table 2 shows the effect of chloroform extract of nauclea latifolia and glibenclamide on blood glucose level of nondiabetic rats. Hot water extracts of the leaves and fruits of nauclea latifolia were assessed. Extracts of the plant have exhibited activity against escherichia coli, shigella flexneri, salmonella typhi and staphylococcus aureus which are responsible for gastroenteritis in children303. Nauclea latifolia contained alkaloid, saponins, flavonoids, cardiac glycosides and steroids while tannins and terpenoids were absent. We will indeed be offering the african herb, nauclea latifolia, stephen buhner has mentioned. Linnaeus originally named it cephalanthus orientalis in the first edition of species plantarum but transferred it to nauclea when he erected that genus in the second. It grows to a maximum of around 30 m 98 ft in height and has large glossy leaves.
Nauclea is a member of the tribe naucleeae and is sister to a clade consisting of burttdavya and sarcocephalus. Files are available under licenses specified on their description page. Nauclea latifolia is a valuable medicinal plant that is widespread in the humid tropical rainforest zone or in savannah woodlands of west and central africa. Bioactive screening and in vitro antioxidant assessment of nauclea latifolia leaf decoction franklyn nonso iheagwam 1, 2, a, emmanuel israel nsedu 1, kazeem oyindamola kayode 1, opeyemi christianah emiloju 1, 2, olubanke olujoke ogunlana 1, 2 and shalom nwodo chinedu 1, 2 1 department of biochemistry, college of science and technology, covenant university, canaanland, p. May 15, 2018 african peach nauclea latifolia is a deciduous evergreen tree native to the savanna forests of continental africa. Latifolia is native to africa and asia gidado et al. Nauclea latifolia smith rubiaceae is a multistemmed shrub or small tree which is widespread in tropical africa and asia. It also publishes academic books and conference proceedings. The teac assay is based on the suppression of the absorbance of radical cations of 2,2azinobis3ethylbenzothiazoline6sulfonate abts by antioxidants in the sample when abts incubates with a peroxidase metmyoglobin and h 2 o 2 43, 44. Direct effects of nauclea latifolia extracts on different gastrointestinal nematodes of sheep is described. Their structures were elucidated based on the analysis of their nmr and ms data. Traditional medicine in many areas of the world relies on the use of a wide variety of plant species. Nhexane, ethyl acetate, butanol and methanol fractions of the ethanolic leaf extract of nauclea latifolia were orally administered once daily for 2 weeks to diabetic rats. The study design consisted of twenty four rats divided into four groups of six rats each.
A 4 ounce bottle should be close to a one month supply. Aspergillus niger is a filamentous ascomycete fungus that is ubiguitous in the environment and has been implicated in opportunistic infections of humans. Nauclea latifolia rubiaceae commonly known as pin cushion tree is. It bears spherical clusters of fragrant flowers that develop into golf ballsized edible but. African peach is also commonly known as african fig and is a member of the rubiaceae coffee family of flowering plants. Despite the acclaimed and documented uses of nauclea latifolia there appears to be a paucity of information on the safety of this plant on the neonatal kidney, as traditional birth attendant in nigeria have used the ethanolic extract of nauclea latifolia stem and root bark in arresting preterm contractions in pregnant women duke, 2008.
The stem bark, the leaves, the roots, and the fruit of this plant are used to treat various types of diseases 2, 3, 4. This study was carried out to investigate the in vitro antioxidant potentials of the leaves and fruits of nauclea latifolia, a straggling shrub or small tree, native to tropical africa and asia. It is widely distributed throughout the forest and tropical forests of benin, burkina faso, cameroon, democratic republic of congo, ghana and nigeria lamidi et al. It is commonly known as pin cushion tree being a straggling shrub or small tree, native to the tropical africa and asia 6.
It normally produces interesting flowers, edible, but not appealing, large red ball fruits with long projecting stamens. Hematological parameters which have been implicated in diabetes mellitus were investigated in this study. How nauclea orientalis is effective for various diseases is listed in repertory format. A research paper, showing the presence of a natural painrelieving opoid in the bark and roots of nauclea latifolia. This tree is known to have various medical uses, particularly by folk medicine men 5. Constituents from nauclea latifolia with antihaemophilus.